Buy Norflurazepam Powder Online | High-Purity Benzodiazepine Research Chemical

Introduction to Buy Norflurazepam Powder

Buy Norflurazepam Powder (N-desalkylflurazepam), designated in pharmacological literature as the primary active metabolite of the classical benzodiazepine flurazepam, is a highly potent, long-acting 1,4-benzodiazepine and a critical reference standard in neuropharmacological and forensic toxicology research. Structurally, it is the N-desalkyl derivative, meaning the N-alkyl side chain has been enzymatically cleaved, leaving the core benzodiazepine ring intact.

In neuropharmacological research, Norflurazepam functions as a positive allosteric modulator (PAM) at the GABA_A receptor, potentiating the inhibitory effects of GABA. Because it lacks the bulky N-alkyl substituent of its parent drug, it provides researchers with a vital baseline tool for studying the structural-activity relationships (SAR) of long-acting benzodiazepines and mapping how N-substitutions alter receptor kinetics and metabolic clearance. Supplied as a high-purity raw powder, this format offers exceptional versatility for laboratories requiring custom volumetric dosing for in-vitro assay preparation and analytical calibration. Note: This product is strictly intended for in-vitro research and analytical purposes only.

Key Features and Benefits – Buy Norflurazepam Powder

• Raw Powder Versatility: Supplied as a pure, raw powder, this format allows researchers to create precise, custom-concentration volumetric solutions tailored to unique in-vitro assay requirements, eliminating the variables of pre-mixed liquids or fixed-dose blisters.
• Long-Acting Metabolite Modeling: Provides researchers with the direct active metabolite of flurazepam, essential for mapping the pharmacokinetic pathways of ultra-long-acting benzodiazepines and their prolonged receptor occupancy.
• Pharmacokinetic Baseline: As the N-desalkyl core, it allows researchers to isolate and study the receptor binding kinetics of the metabolite itself, contrasting it against N-alkylated analogs to map how side-chain bulk affects subunit selectivity and duration of action.
• Analytical Standard: Essential for forensic and analytical laboratories requiring pure reference materials to validate LC/MS and GC/MS instruments, ensuring accurate detection of flurazepam ingestion in biological matrices.
• HCl Salt Stability: Supplied as a stable hydrochloride (HCl) crystalline powder, ensuring exceptional physical stability, precise measurability, and safe handling compared to unstable freebase oils.

Product Specifications

• Chemical Name: 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one hydrochloride
• Common Designation: Norflurazepam / N-Desalkylflurazepam
• CAS Number: 3407-95-0 (Freebase)
• Class: 1,4-Benzodiazepine / GABA_A PAM / Long-Acting Metabolite / Research Chemical
• Form: Crystalline Powder / Raw Synthetic Powder (Hydrochloride Salt)
• Purity: ≥ 98% (Verified by Independent Third-Party Testing)
• Appearance: White to off-white fine crystalline powder
• Storage Requirements: Store in a cool, dry, dark environment (ideally -20°C for long-term archival). Keep container tightly sealed under inert gas to prevent hygroscopic absorption and oxidation.
• Solubility: Freely soluble in water, DMSO, and ethanol.

Applications and Usage

Norflurazepam Powder is exclusively designated for in-vitro (outside a living organism) research and analytical applications. Common laboratory applications include:

• GABA_A Receptor Binding Assays: Investigating the compound’s affinity and efficacy as a positive allosteric modulator at the benzodiazepine binding site on GABA_A receptors, comparing its binding kinetics to its parent compound (flurazepam) and other long-acting analogs.
• Metabolite Pharmacokinetic Profiling: Utilizing Norflurazepam as a reference standard to map the metabolic clearance, half-life, and accumulation potential of N-desalkyl benzodiazepine metabolites in hepatocyte and blood plasma models.
• Forensic Toxicology Calibration: Utilizing Norflurazepam as a certified reference material (CRM) for LC/MS and GC/MS spectroscopy to validate analytical instruments, establish limits of detection, and confirm flurazepam ingestion in biological matrices.
• Structural-Activity Relationship (SAR) Mapping: Contrasting the pharmacodynamic effects of the desalkyl core (Norflurazepam) versus N-alkylated flurazepams to isolate how side-chain bulk affects subunit selectivity and onset/duration of action.

Disclaimer: This product is not for human or veterinary consumption. It must only be handled in controlled laboratory environments by qualified professionals.

Purity and Testing

We guarantee a purity level of ≥ 98% for our Norflurazepam Powder. Every batch undergoes rigorous, independent third-party testing to verify chemical identity, absolute purity, and the absence of dangerous residual solvents, heavy metals, or unreacted precursors. Because benzodiazepines are a highly regulated and counterfeited class, we perform exhaustive screening to ensure the absolute absence of dangerous substituted benzodiazepine contaminants (such as etizolam, flualprazolam, or flubromazolam). Certificates of Analysis (CoA) and Safety Data Sheets (SDS) are provided upon request.

Safety and Handling

WARNING: NORFLURAZEPAM IS A HIGHLY POTENT CENTRAL NERVOUS SYSTEM DEPRESSANT. EXTREME CAUTION IS REQUIRED.

• Personal Protective Equipment (PPE): Must wear nitrile gloves, chemical-resistant safety goggles, and a P100 particulate respirator when weighing or transferring the powder.
• Ventilation: Handling must only occur within a certified chemical fume hood to prevent the inhalation of aerosolized particles.
• Accidental Exposure: If skin contact occurs, wash thoroughly with soap and water immediately. Seek medical attention if physiological effects occur. Note: Opioid antagonists like Naloxone are generally ineffective against benzodiazepine toxicity; flumazenil is the specific antagonist, but may precipitate seizures.
• Hygiene: Remove contaminated clothing immediately and wash hands thoroughly after handling, even when PPE is utilized.
• Secure Storage: Keep powder locked away in a secure, access-controlled laboratory cabinet, out of reach of unauthorized personnel.

Global Shipping and Discreet Delivery

• Global Reach: We ship Norflurazepam Powder internationally, in strict compliance with international shipping regulations.
• Discreet Packaging: All orders are dispatched in unmarked, tamper-evident, and odor-proof packaging. The outer packaging does not indicate the nature of the contents.
• Rapid Processing: Orders are processed and shipped within 24 hours of cleared payment. We offer standard and express courier options with full end-to-end tracking.
• Secure Handling: Powders are double-sealed in moisture-barrier bags and placed within sturdy outer containers to prevent damage during transit.

Why Choose Us To Buy Norflurazepam Powder?

• Uncompromising Quality: We work directly with top-tier chemical synthesis laboratories and verify every batch in-house and via third-party labs before it reaches you.
• Total Transparency: We provide full analytical data. What is on the label is exactly what is in the bag—no fillers, no impurities, no compromises.
• Expert Customer Support: Our support team understands the nuances of research chemicals and is ready to assist with CoA requests, shipping inquiries, and technical questions.
• Secure Transactions: We utilize SSL encryption and accept secure, discreet payment methods, including major cryptocurrencies (Bitcoin, Monero, Ethereum) and secure bank transfers.

Legal and Safety Compliance

Norflurazepam Powder is sold strictly as a research chemical and is not approved by the FDA, EMA, or any equivalent regulatory body for human or veterinary use.

It is the sole responsibility of the purchaser to ensure that the acquisition, possession, and use of Norflurazepam comply with all local, state, national, and international laws. Warning: Norflurazepam is a potent central nervous system depressant and long-acting GABA_A agonist. Ingestion can cause severe, life-threatening psychological and physiological effects, including profound sedation, respiratory depression, coma, and death. It may fall under federal analogue acts or specific benzodiazepine legislation in various jurisdictions. We do not ship to regions where this compound is explicitly prohibited. By purchasing from us, you affirm that you are a qualified researcher or institutional buyer over the age of 18, and you assume all legal liability for the product upon delivery.

Frequently Asked Questions (FAQ)

Q1: What is Norflurazepam?
A: Norflurazepam (N-desalkylflurazepam) is a long-acting 1,4-benzodiazepine. It acts as a positive allosteric modulator at the GABA_A receptor. Crucially, it is the primary active metabolite of flurazepam, meaning it is the chemical compound that remains after the body enzymatically breaks down flurazepam.

Q2: What makes Norflurazepam different from Flurazepam?
A: Flurazepam features a bulky N-alkyl side chain that causes rapid receptor binding but quick metabolic clearance. Norflurazepam lacks this side chain (it is the “desalkyl” version). This structural difference makes Norflurazepam ultra-long-acting with a much slower clearance rate, providing a vital tool for comparative SAR (Structural-Activity Relationship) and pharmacokinetic research.

Q3: Why choose the powder form over blisters or pellets?
A: The raw powder format offers maximum versatility for laboratory researchers. It allows for the creation of highly specific, custom-concentration volumetric solutions tailored to unique in-vitro assay requirements, streamlining high-throughput screening without the limitations of fixed-dose units.

Q4: Can Norflurazepam Powder be consumed?
A: Absolutely not. Norflurazepam is a highly potent, long-acting CNS depressant. Ingestion can cause profound, long-lasting sedation, respiratory depression, and death. It is strictly for in-vitro laboratory and analytical research and is strictly prohibited for human consumption.

Q5: Do you provide a Certificate of Analysis (CoA)?
A: Yes. We provide a comprehensive CoA—including HPLC, GC/MS, and NMR data—for every batch we sell. This guarantees the identity, purity, and mass of the compound.

Q6: Is it legal to buy Norflurazepam in my country?
A: Legality varies drastically. Because it is a 1,4-benzodiazepine and the active metabolite of a scheduled drug (Flurazepam), it is often controlled under analogue acts or specific NPS/benzodiazepine bans. We cannot provide legal advice. It is your responsibility to research your local laws regarding this compound before placing an order.

Q7: How should I store Norflurazepam Powder for long-term research?
A: For maximum longevity, store Norflurazepam powder in an airtight, amber glass vial under an inert gas (like Argon) in a freezer set to -20°C. Keep away from direct sunlight, heat, and moisture.